What is a typical tidal volume setting for volume-controlled mechanical ventilation in an adult?

• A. 2-4 mL/kg
• B. 12-15 mL/kg
• C. 6-8 mL/kg
• D. 8-10 mL/kg

Answer: (C)

In volume-controlled ventilation, the tidal volume is set based on predicted body weight to provide adequate ventilation while protecting the lungs from injury. A typical target is about 6 to 8 mL per kilogram of predicted body weight. This range helps ensure enough CO2 is cleared without overdistending the alveoli. Lowering below 6 mL/kg can lead to insufficient ventilation and hypercapnia, while delivering well above 8 mL/kg increases the risk of volutrauma and barotrauma. In practice, 6–8 mL/kg PBW is the standard starting point for most adult patients, with adjustments guided by blood gases and lung condition.